Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13451264 | 0.88 | TDP1 (0.47) | TDP1KDM4EHTTMAPTKDM1A | |
| SCHEMBL13451265 | 0.80 | GAA (0.39) | TDP1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL4721218 | 0.78 | HTT (0.49) | HTTKDM1AALDH1A1GNAI3GNAO1 | |
| SCHEMBL3699860 | 0.77 | KDM1A (0.33) | TDP1HTTKDM1AGLAGNAI3 | |
| SCHEMBL3712866 | 0.77 | HTR4 (0.34) | TDP1HTTKDM1AGLAALDH1A1 | |
| SCHEMBL13567506 | 0.76 | KDM1A (0.37) | HTTKDM1AGNAI3GNAO1GNAI1 | |
| Hydrazine SCHEMBL8557171 | 0.74 | HTT (0.46) | HTTKDM1AALDH1A1GNAI3GNAO1 | |
| SCHEMBL28245251 | 0.74 | GNAI3 (0.59) | HTTKDM1AKMT2AALDH1A1GNAI3 | |
| SCHEMBL9126435 | 0.74 | KDM1A (0.38) | HTTKDM1AGNAI3GNAO1GNAI1 | |
| Bromide SCHEMBL28507361 | 0.73 | GNAI3 (0.58) | HTTKDM1AKMT2AALDH1A1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |