Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3699860 | 0.86 | KDM1A (0.33) | HTR4KDM1ATDP1HTTGLA | |
| SCHEMBL935171 | 0.83 | HTT (0.36) | KDM1AHTTGNAI3GNAO1GNAI1 | |
| SCHEMBL935537 | 0.79 | GNAI3 (0.53) | GNAI3GNAO1GNAI1 | |
| SCHEMBL3706388 | 0.78 | HTR4 (0.34) | HTR4KDM1AGLACYP2C19ALDH1A1 | |
| SCHEMBL3709883 | 0.77 | HTT (0.36) | KDM1AHTTGNAI3GNAO1GNAI1 | |
| SCHEMBL14467701 | 0.77 | TDP1 (0.41) | HTR4KDM1ATDP1HTTGLA | |
| SCHEMBL30998792 | 0.76 | TDP1 (0.46) | KDM1ATDP1LMNACYP2C19HPGD | |
| SCHEMBL33525084 | 0.74 | HTT (0.63) | HTTGLAALDH1A1 | |
| SCHEMBL4721218 | 0.74 | HTT (0.49) | KDM1ALMNAHTTHPGDGNAI3 | |
| SCHEMBL125043 | 0.73 | SMN1; SMN2 (0.48) | TDP1LMNAHPGDDUSP3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357755-B2 | Cross-linkable organosilicon-based compositions | WACKER CHEMIE AG (DE) | 2013-01-22 | — | — | US | disclosed |
| US-20120123048-A1 | CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS | WACKER CHEMIE AG (DE) | 2012-05-17 | — | — | US | disclosed |