Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881665 | 0.85 | HRH3 (0.36) | HRH3KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL10097712 | 0.84 | HPGD (0.39) | HRH3KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL10252659 | 0.75 | GRIK2 (0.54) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL13152364 | 0.74 | KIF11 (0.42) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL14467915 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDMAPTPARP1 | |
| SCHEMBL13152304 | 0.72 | GRIK2 (0.40) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL13152317 | 0.72 | TDP1 (0.46) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL13152272 | 0.72 | GRIK2 (0.39) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL12109159 | 0.72 | GRIK2 (0.39) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL20315357 | 0.72 | HRH3 (0.41) | HRH3KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |