Juarezic Acid

Juarezic Acid

SCHEMBL30239689

O=C(O)C=CC=Cc1ccccc1.[Na]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.68
HDAC4 P56524 3/20 0.68
HDAC1 Q13547 3/20 0.68
HDAC2 Q92769 3/20 0.68
HDAC8 Q9BY41 3/20 0.68
HDAC6 Q9UBN7 3/20 0.68
HDAC7 Q8WUI4 2/20 0.68
HDAC10 Q969S8 2/20 0.68
HDAC11 Q96DB2 2/20 0.68
HDAC9 Q9UKV0 2/20 0.68
HDAC5 Q9UQL6 2/20 0.68
TNKS O95271 1/20 0.68
HCAR2 Q8TDS4 1/20 0.68
TNKS2 Q9H2K2 1/20 0.68
MAOB P27338 8/20 0.61
ALDH1A1 P00352 3/20 0.56
MAPT P10636 3/20 0.56
CYP1A2 P05177 3/20 0.56
LMNA P02545 3/20 0.56
CYP2D6 P10635 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Juarezic Acid SCHEMBL436113 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL144681 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL474728 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL11522747 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL144680 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL15119 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL560728 0.96 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL3280210 0.96 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL2335383 0.96 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL4304844 0.96 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115777700-B Suspending agent containing metribuzin and haloxyfop-methyl and preparation method thereof 山东润博生物科技有限公司 2024-11-08 CN claimed
CN-116098155-B Suspending agent containing sulfenamide and metazachlor and preparation method thereof 山东潍坊润丰化工股份有限公司 2024-09-27 CN claimed
CN-116982625-A Suspending agent containing halofop-butyl and flumioxazin and preparation method thereof 山东潍坊润丰化工股份有限公司 2023-11-03 CN claimed
CN-116439237-A Pesticide sterilization wettable powder and preparation method and application thereof 山东润博生物科技有限公司 2023-07-18 CN claimed
CN-115777700-B Suspending agent containing metribuzin and haloxyfop-methyl and preparation method thereof 山东润博生物科技有限公司 2024-11-08 CN disclosed
CN-116098155-B Suspending agent containing sulfenamide and metazachlor and preparation method thereof 山东潍坊润丰化工股份有限公司 2024-09-27 CN disclosed
CN-116982625-A Suspending agent containing halofop-butyl and flumioxazin and preparation method thereof 山东潍坊润丰化工股份有限公司 2023-11-03 CN disclosed
CN-116439237-A Pesticide sterilization wettable powder and preparation method and application thereof 山东润博生物科技有限公司 2023-07-18 CN disclosed
CN-116098155-A Suspending agent containing sulfenamide and metazachlor and preparation method thereof 山东潍坊润丰化工股份有限公司 2023-05-12 CN disclosed
CN-115777700-A Suspending agent containing metribuzin and topramezone and preparation method thereof 山东润博生物科技有限公司 2023-03-14 CN disclosed