Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111324 | 0.88 | CYP2C9 (0.45) | CYP2C9PDE4AALDH1A1MAPTLMNA | |
| SCHEMBL11111329 | 0.88 | CYP2C9 (0.45) | CYP2C9PDE4AALDH1A1MAPTLMNA | |
| SCHEMBL14469047 | 0.84 | CYP2C9 (0.41) | CYP2C9PDE4AALDH1A1MAPTLMNA | |
| SCHEMBL14469046 | 0.82 | FDPS (0.41) | CYP2C9ALDH1A1MAPTLMNAALOX5 | |
| SCHEMBL25989553 | 0.82 | PTGES (0.37) | CYP2C9PDE4AALDH1A1MAPTLMNA | |
| SCHEMBL19497966 | 0.81 | ESR2 (0.54) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL22040028 | 0.79 | CYP2C9 (0.40) | CYP2C9PDE4AALDH1A1MAPTLMNA | |
| SCHEMBL18873612 | 0.79 | CYP2C9 (0.43) | CYP2C9PDE4AALDH1A1MAPTLMNA | |
| SCHEMBL19497969 | 0.79 | CYP2C9 (0.43) | CYP2C9PDE4AALDH1A1MAPTLMNA | |
| SCHEMBL19504849 | 0.79 | CYP2C9 (0.46) | CYP2C9ALDH1A1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247355-B2 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |