Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469045 | 0.84 | CYP2C9 (0.41) | CYP2C9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14449492 | 0.83 | PRMT5 (0.41) | CYP2C9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10764754 | 0.81 | CYP2C9 (0.50) | CYP2C9MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10764762 | 0.81 | CYP2C9 (0.50) | CYP2C9MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13402048 | 0.80 | KDM1A (0.39) | CYP2C9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10765768 | 0.79 | RAB9A (0.48) | CYP2C9MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10765763 | 0.79 | RAB9A (0.48) | CYP2C9MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11113013 | 0.79 | ALDH1A1 (0.45) | CYP2C9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11113008 | 0.79 | ALDH1A1 (0.45) | CYP2C9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10043320 | 0.79 | KDM1A (0.38) | CYP2C9PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247355-B2 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |