Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469179 | 0.86 | ADRB2 (0.54) | ADRB2MEN1KMT2AKDM4ETSHR | |
| SCHEMBL14469462 | 0.77 | FAAH (0.50) | KDM4EPOLBALDH1A1FAAH | |
| SCHEMBL14469559 | 0.77 | KDM4E (0.46) | ADRB2MEN1KMT2AKDM4ETSHR | |
| SCHEMBL8228179 | 0.77 | ADRB2 (0.77) | ADRB2MEN1KMT2AKDM4ETSHR | |
| SCHEMBL14469477 | 0.77 | KMT2A (0.58) | ADRB2MEN1KMT2AKDM4ETSHR | |
| SCHEMBL14469464 | 0.77 | MEN1 (0.45) | ADRB2MEN1KMT2AKDM4ETSHR | |
| SCHEMBL14456715 | 0.77 | MEN1 (0.69) | ADRB2MEN1KMT2AKDM4ETSHR | |
| SCHEMBL14469115 | 0.76 | MEN1 (0.49) | ADRB2MEN1KMT2AKDM4ETSHR | |
| SCHEMBL14469549 | 0.75 | KDM4E (0.50) | MEN1KMT2AKDM4ETSHRALDH1A1 | |
| SCHEMBL14456710 | 0.75 | ADRB2 (0.67) | ADRB2MEN1KMT2ATSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |