Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469240 | 0.86 | CNR1 (0.58) | LMNAGAAKMT2ACNR1F10 | |
| SCHEMBL14469366 | 0.84 | CNR1 (0.58) | ALDH1A1LMNAGAACNR1F13A1 | |
| SCHEMBL14469582 | 0.83 | CNR1 (0.47) | HTTCNR1CHRM1F10NPSR1 | |
| SCHEMBL14469583 | 0.82 | POLB (0.53) | ALDH1A1HTTLMNAGAAKMT2A | |
| SCHEMBL14469581 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAGAACNR1F13A1 | |
| SCHEMBL14469235 | 0.81 | CNR1 (0.45) | ALDH1A1HTTGAAKMT2ACNR1 | |
| SCHEMBL14469592 | 0.79 | LSS (0.42) | ALDH1A1HTTLMNAGAAMAPT | |
| SCHEMBL14469587 | 0.79 | L3MBTL1 (0.53) | ALDH1A1GAACNR1F13A1TGM2 | |
| SCHEMBL14469197 | 0.78 | CNR1 (0.44) | ALDH1A1HTTLMNAGAAKMT2A | |
| SCHEMBL14469580 | 0.76 | L3MBTL1 (0.41) | ALDH1A1GAAMAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |