Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469582 | 0.91 | CNR1 (0.47) | CNR1NPSR1F10POLB | |
| SCHEMBL14469366 | 0.91 | CNR1 (0.58) | CNR1NPSR1GAAF10POLB | |
| SCHEMBL14469583 | 0.87 | POLB (0.53) | CNR1NPSR1GAAPOLBLMNA | |
| SCHEMBL14469199 | 0.86 | ALDH1A1 (0.47) | CNR1NPSR1GAAF10POLB | |
| SCHEMBL14469581 | 0.86 | ALDH1A1 (0.45) | CNR1NPSR1GAAPOLBLMNA | |
| SCHEMBL14469235 | 0.86 | CNR1 (0.45) | CNR1NPSR1GAAPOLBKMT2A | |
| SCHEMBL14469587 | 0.83 | L3MBTL1 (0.53) | CNR1NPSR1GAA | |
| SCHEMBL14469197 | 0.82 | CNR1 (0.44) | CNR1NPSR1GAAPOLBMEN1 | |
| SCHEMBL14469589 | 0.82 | TP53 (0.45) | CNR1NPSR1LMNA | |
| SCHEMBL14469234 | 0.82 | ALDH1A1 (0.38) | CNR1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |