Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469194 | 0.88 | ALDH1A1 (0.38) | ALDH1A1GAASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL14469197 | 0.83 | CNR1 (0.44) | ALDH1A1GAASMN1; SMN2HTTTSHR | |
| SCHEMBL14469240 | 0.82 | CNR1 (0.58) | GAACNR1KMT2A | |
| SCHEMBL14469581 | 0.82 | ALDH1A1 (0.45) | ALDH1A1GAAL3MBTL1TSHRCNR1 | |
| SCHEMBL14469583 | 0.82 | POLB (0.53) | ALDH1A1GAASMN1; SMN2L3MBTL1HTT | |
| SCHEMBL14469586 | 0.81 | CNR1 (0.41) | ALDH1A1GAAL3MBTL1KDM4ETSHR | |
| SCHEMBL14469235 | 0.80 | CNR1 (0.45) | ALDH1A1GAASMN1; SMN2HTTCNR1 | |
| SCHEMBL14469366 | 0.80 | CNR1 (0.58) | ALDH1A1GAAL3MBTL1TSHRCNR1 | |
| SCHEMBL14469294 | 0.79 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2TSHRCNR1KMT2A | |
| SCHEMBL14469589 | 0.79 | TP53 (0.45) | ALDH1A1MAPTL3MBTL1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |