Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469115 | 0.88 | MEN1 (0.49) | ALDH1A1KDM4ESIGMAR1MEN1KMT2A | |
| SCHEMBL14469562 | 0.87 | L3MBTL1 (0.47) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL14469179 | 0.86 | ADRB2 (0.54) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL14469474 | 0.86 | MTNR1B (0.49) | ALDH1A1KDM4ETDP1SIGMAR1MTNR1B | |
| SCHEMBL14469477 | 0.85 | KMT2A (0.58) | ALDH1A1KDM4EMEN1KMT2AALOX15 | |
| SCHEMBL14469464 | 0.85 | MEN1 (0.45) | ALDH1A1KDM4EMEN1KMT2AALOX15 | |
| SCHEMBL14469459 | 0.85 | KDM4E (0.56) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL14469480 | 0.85 | KMT2A (0.54) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL14469190 | 0.85 | CYP3A4 (0.48) | MEN1KMT2ATSHR | |
| SCHEMBL14469285 | 0.84 | L3MBTL1 (0.44) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |