Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469584 | 0.90 | CNR1 (0.57) | CNR1F10ALDH1A1MEN1LMNA | |
| SCHEMBL14469593 | 0.87 | CNR1 (0.45) | CNR1HTTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL14469582 | 0.83 | CNR1 (0.47) | CNR1HTTSMN1; SMN2CHRM1F10 | |
| SCHEMBL14469240 | 0.74 | CNR1 (0.58) | CNR1F10MEN1LMNAKMT2A | |
| SCHEMBL14456971 | 0.73 | HTT (0.51) | CNR1HTTSMN1; SMN2CHRM1F10 | |
| SCHEMBL14469197 | 0.73 | CNR1 (0.44) | CNR1HTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL14469366 | 0.72 | CNR1 (0.58) | CNR1F10ALDH1A1LMNANPSR1 | |
| SCHEMBL14469583 | 0.71 | POLB (0.53) | CNR1HTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14469235 | 0.70 | CNR1 (0.45) | CNR1HTTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL14469581 | 0.68 | ALDH1A1 (0.45) | CNR1ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |