Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469592 | 0.85 | LSS (0.42) | LSSF13A1TGM2TGM1HSD17B10 | |
| SCHEMBL14469583 | 0.73 | POLB (0.53) | LSSF13A1TGM2TGM1TSHR | |
| SCHEMBL14469184 | 0.72 | POLB (0.57) | LSSF13A1TGM2TGM1TSHR | |
| SCHEMBL14469235 | 0.72 | CNR1 (0.45) | POLBHTTGAAKMT2AALDH1A1 | |
| SCHEMBL14469192 | 0.71 | MEN1 (0.59) | TSHRLMNAPOLBHTTMEN1 | |
| SCHEMBL14469586 | 0.71 | CNR1 (0.41) | LSSTSHRLMNAMAPK1POLB | |
| SCHEMBL14469200 | 0.69 | POLB (0.46) | HSD17B10LMNAMAPK1POLBALDH1A1 | |
| SCHEMBL14469366 | 0.69 | CNR1 (0.58) | F13A1TGM2TGM1TSHRLMNA | |
| SCHEMBL14469581 | 0.69 | ALDH1A1 (0.45) | F13A1TGM2TGM1TSHRLMNA | |
| SCHEMBL14469195 | 0.69 | CHRM1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |