Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 16/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14457008 | 0.85 | ACKR3 (0.61) | ACKR3DRD4ALDH1A1 | |
| SCHEMBL14469123 | 0.76 | ADRB2 (0.45) | — | |
| SCHEMBL13588409 | 0.70 | TEAD1 (0.47) | DRD4 | |
| SCHEMBL14469464 | 0.70 | MEN1 (0.45) | ALDH1A1 | |
| SCHEMBL14456856 | 0.70 | ACKR3 (0.58) | ACKR3DRD4 | |
| SCHEMBL14469190 | 0.69 | CYP3A4 (0.48) | — | |
| SCHEMBL14469179 | 0.69 | ADRB2 (0.54) | ALDH1A1 | |
| SCHEMBL14469115 | 0.69 | MEN1 (0.49) | ALDH1A1 | |
| SCHEMBL14469477 | 0.68 | KMT2A (0.58) | ALDH1A1 | |
| SCHEMBL19493176 | 0.67 | SIGMAR1 (0.57) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |