Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 9/20 | 0.44 |
| ▸ | UBE2M | P61081 | 8/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003430 | 0.81 | SIGMAR1 (0.56) | KCNH2MCHR1DCUN1D1UBE2MSIGMAR1 | |
| SCHEMBL14469472 | 0.79 | FAAH (0.51) | KMT2A | |
| SCHEMBL14469115 | 0.74 | MEN1 (0.49) | SIGMAR1MEN1KMT2A | |
| SCHEMBL14469477 | 0.73 | KMT2A (0.58) | MEN1KMT2A | |
| SCHEMBL14469464 | 0.73 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL14469179 | 0.72 | ADRB2 (0.54) | MEN1KMT2A | |
| SCHEMBL4980678 | 0.72 | UBE2M (0.54) | TEAD1KCNH2MCHR1DCUN1D1UBE2M | |
| SCHEMBL14469465 | 0.71 | ALDH1A1 (0.49) | KCNH2MEN1KMT2A | |
| SCHEMBL14078567 | 0.70 | MGLL (0.47) | MEN1KMT2A | |
| SCHEMBL14469590 | 0.70 | ACKR3 (0.52) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902046-B1 | PIPERIDINE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORP (US) | 2009-12-02 | — | — | EP | disclosed |