Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 11/20 | 0.43 |
| ▸ | PGR | P06401 | 5/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23964558 | 0.83 | NR3C1 (0.43) | NR3C1NR3C2PGRNR1I2ALDH1A1 | |
| SCHEMBL9446144 | 0.81 | ALDH1A1 (0.61) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL3804565 | 0.80 | NR3C1 (0.41) | NR3C1NR3C2PGRNR1I2ALDH1A1 | |
| SCHEMBL2437476 | 0.79 | ALOX15 (0.44) | PGRNR1I2ALDH1A1LMNACYP2C9 | |
| SCHEMBL395584 | 0.78 | ALDH1A1 (0.61) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL11314238 | 0.78 | ALDH1A1 (0.45) | NR3C1NR3C2PGRNR1I2ALDH1A1 | |
| SCHEMBL6153419 | 0.78 | ALOX15 (0.42) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL30621344 | 0.76 | ALDH1A1 (0.59) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL23772707 | 0.76 | NR1I2 (0.39) | NR3C1NR3C2PGRNR1I2ALDH1A1 | |
| SCHEMBL3882399 | 0.75 | NR3C2 (0.53) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675839-B1 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | BOEHRINGER INGELHEIM PHARMA (US) | 2007-07-11 | — | — | EP | disclosed |