Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 12/20 | 0.77 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373344 | 0.88 | CXCR3 (0.81) | CXCR3BRSK1AURKBCLK2DYRK1A | |
| SCHEMBL14470553 | 0.87 | CXCR3 (0.80) | CXCR3BRSK1AURKBCLK2DYRK1A | |
| SCHEMBL14373345 | 0.87 | CXCR3 (0.80) | CXCR3BRSK1AURKBCLK2DYRK1A | |
| SCHEMBL14373346 | 0.87 | CXCR3 (1.00) | CXCR3BRSK1AURKBCLK2DYRK1A | |
| SCHEMBL14470531 | 0.84 | BRSK1 (0.63) | CXCR3BRSK1AURKBCLK2DYRK1A | |
| SCHEMBL14470746 | 0.82 | CXCR3 (0.56) | CXCR3BRSK1AURKBCLK2DYRK1A | |
| SCHEMBL14470749 | 0.82 | CXCR3 (0.53) | CXCR3BRSK1AURKBCLK2DYRK1A | |
| SCHEMBL14373366 | 0.81 | CXCR3 (0.70) | CXCR3BRSK1AURKBCLK2DYRK1A | |
| SCHEMBL14373367 | 0.80 | CXCR3 (0.69) | CXCR3BRSK1AURKBCLK2DYRK1A | |
| SCHEMBL14373368 | 0.80 | CXCR3 (0.86) | CXCR3BRSK1AURKBCLK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084728-A2 | 2-IMINO-BENZIMIDAZOLES | ABBOTT LABORATORIES (US) | 2007-07-26 | — | — | WO | disclosed |