Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 12/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373361 | 0.90 | RAB9A (0.57) | CXCR3RAB9ANPC1KMT2ABRSK1 | |
| SCHEMBL14373363 | 0.89 | CXCR3 (0.67) | CXCR3KMT2ACLK2DYRK1ACLK4 | |
| SCHEMBL14373362 | 0.89 | CXCR3 (0.62) | CXCR3RAB9ANPC1KMT2ABRSK1 | |
| SCHEMBL14470554 | 0.82 | CXCR3 (0.77) | CXCR3RAB9ANPC1KMT2ABRSK1 | |
| SCHEMBL14373364 | 0.79 | CXCR3 (0.53) | CXCR3RAB9ANPC1KMT2ACLK2 | |
| SCHEMBL14470746 | 0.79 | CXCR3 (0.56) | CXCR3RAB9ANPC1KMT2ABRSK1 | |
| SCHEMBL14373340 | 0.77 | RAB9A (0.62) | CXCR3RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL14373341 | 0.76 | CXCR3 (0.67) | CXCR3RAB9ANPC1KMT2ABRSK1 | |
| SCHEMBL14470531 | 0.76 | BRSK1 (0.63) | CXCR3RAB9ANPC1KMT2ABRSK1 | |
| SCHEMBL14373342 | 0.76 | CXCR3 (0.72) | CXCR3KMT2ACLK2DYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084728-A2 | 2-IMINO-BENZIMIDAZOLES | ABBOTT LABORATORIES (US) | 2007-07-26 | — | — | WO | disclosed |