Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 12/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373327 | 0.88 | RAB9A (0.64) | CXCR3RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL14373328 | 0.87 | CXCR3 (0.69) | CXCR3RAB9ANPC1KMT2ABRSK1 | |
| SCHEMBL14373329 | 0.87 | CXCR3 (0.75) | CXCR3RAB9ANPC1KMT2ACLK2 | |
| SCHEMBL14470554 | 0.82 | CXCR3 (0.77) | CXCR3RAB9ANPC1KMT2ABRSK1 | |
| SCHEMBL14470749 | 0.79 | CXCR3 (0.53) | CXCR3RAB9ANPC1KMT2ABRSK1 | |
| SCHEMBL14470531 | 0.76 | BRSK1 (0.63) | CXCR3RAB9ANPC1KMT2ABRSK1 | |
| SCHEMBL14373331 | 0.75 | CXCR3 (0.58) | CXCR3RAB9ANPC1KMT2ACLK2 | |
| SCHEMBL14373299 | 0.72 | CXCR3 (0.75) | CXCR3RAB9ANPC1KMT2ABRSK1 | |
| SCHEMBL14373284 | 0.72 | CXCR3 (0.80) | CXCR3RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL14470564 | 0.71 | CXCR3 (0.78) | CXCR3RAB9ANPC1KMT2ABRSK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084728-A2 | 2-IMINO-BENZIMIDAZOLES | ABBOTT LABORATORIES (US) | 2007-07-26 | — | — | WO | disclosed |