Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3854539 | 0.86 | MAPT (0.48) | GSK3BALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL14758551 | 0.85 | ALPL (0.37) | CXCR3ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17792927 | 0.78 | POLB (0.42) | ALDH1A1MAPTHTTCYP3A4CYP2D6 | |
| SCHEMBL6939314 | 0.74 | GSK3B (0.47) | CXCR3GSK3BALDH1A1MAPTRAB9A | |
| Bromide SCHEMBL3854344 | 0.73 | MAPT (0.48) | CXCR3GSK3BALDH1A1MAPTRAB9A | |
| Bromide SCHEMBL11567156 | 0.71 | MEN1 (0.48) | GSK3BALDH1A1MAPTHTTLMNA | |
| SCHEMBL28841430 | 0.70 | ALDH1A1 (0.48) | CXCR3GSK3BALDH1A1MAPTRAB9A | |
| SCHEMBL11995108 | 0.69 | ALDH1A1 (0.43) | ALDH1A1MAPTUSP2LMNAKMT2A | |
| SCHEMBL15893962 | 0.69 | ALDH1A1 (0.60) | CXCR3GSK3BALDH1A1MAPTRAB9A | |
| SCHEMBL15298888 | 0.69 | ALDH1A1 (0.70) | ALDH1A1MAPTRAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084728-A2 | 2-IMINO-BENZIMIDAZOLES | ABBOTT LABORATORIES (US) | 2007-07-26 | — | — | WO | disclosed |