Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.42 |
| ▸ | F12 | P00748 | 5/20 | 0.39 |
| ▸ | MGAM | O43451 | 5/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | SI | P14410 | 5/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218121 | 0.79 | ASAH1 (0.50) | ALDH1A1ASAH1F12MGAMAMY1A | |
| SCHEMBL20928041 | 0.79 | ASAH1 (0.53) | ALDH1A1HSD17B10ASAH1F12MGAM | |
| SCHEMBL14494257 | 0.77 | ASAH1 (0.43) | ALDH1A1HSD17B10ASAH1F12MGAM | |
| SCHEMBL22101596 | 0.72 | ASAH1 (0.56) | ALDH1A1HSD17B10ASAH1F12MGAM | |
| SCHEMBL20156704 | 0.72 | ASAH1 (0.51) | ALDH1A1HSD17B10ASAH1F12MGAM | |
| SCHEMBL14470768 | 0.70 | ASAH1 (0.40) | HSD17B10ASAH1F12MGAMAMY1A | |
| SCHEMBL14470767 | 0.69 | ASAH1 (0.41) | ALDH1A1HSD17B10ASAH1F12MGAM | |
| SCHEMBL14470772 | 0.69 | ASAH1 (0.41) | ALDH1A1HSD17B10ASAH1F12MGAM | |
| SCHEMBL14470770 | 0.69 | ASAH1 (0.39) | HSD17B10ASAH1F12MGAMAMY1A | |
| SCHEMBL29008120 | 0.69 | ASAH1 (0.52) | ALDH1A1HSD17B10ASAH1F12MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167426-A1 | Compounds for the treatment of inflammatory disorders and microbial diseases | SCHERING CORPORATION | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167426-A1 | Compounds for the treatment of inflammatory disorders and microbial diseases | MMP12, ADAMTS1, ADAM33 | ALDH1A1 1502/4885HSD17B10 581/4885THRB 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.