Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2971365 | 0.82 | MEN1 (0.42) | CSNK2A1F2RMAPTHTTNPC1 | |
| SCHEMBL9085956 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17877022 | 0.80 | HPGD (0.53) | ALDH1A1CSNK2A1F2RMAPTNPC1 | |
| SCHEMBL10389402 | 0.80 | MEN1 (0.50) | ALDH1A1CSNK2A1HTTMEN1KMT2A | |
| SCHEMBL27992485 | 0.79 | MAPT (0.49) | ALDH1A1CSNK2A1F2RMAPTHTT | |
| SCHEMBL10325047 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL30612298 | 0.79 | ALDH1A1 (0.54) | ALDH1A1F2RMAPTHTTNPC1 | |
| SCHEMBL12261016 | 0.78 | CSNK2A1 (0.62) | ALDH1A1CSNK2A1MAPTHTTNPC1 | |
| SCHEMBL136961 | 0.78 | F2R (0.47) | CSNK2A1F2RMAPTHTTNPC1 | |
| SCHEMBL30844550 | 0.78 | F2R (0.47) | CSNK2A1F2RMAPTHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155756-A1 | Treatment of chemokine mediated diseases | SCHERING CORPORATION | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155756-A1 | Treatment of chemokine mediated diseases | CXCR3, ACKR3, CCL11 | ALDH1A1 1552/4885CSNK2A1 2546/4885F2R 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.