Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29413990 | 0.83 | NNMT (0.46) | KDM4EL3MBTL1 | |
| SCHEMBL18300431 | 0.83 | MAPT (0.32) | GAARAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL18300430 | 0.83 | MAPT (0.32) | GAARAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL15285101 | 0.78 | P4HA1 (0.46) | MAPTHSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL16688436 | 0.78 | HDAC3 (0.38) | GAARAB9ANPC1LMNAMAPT | |
| SCHEMBL14471374 | 0.77 | GAA (0.41) | GAARAB9ANPC1LMNATP53 | |
| SCHEMBL1727208 | 0.77 | RAB9A (0.41) | GAARAB9ANPC1LMNATP53 | |
| SCHEMBL1727207 | 0.77 | RAB9A (0.41) | GAARAB9ANPC1LMNATP53 | |
| SCHEMBL16560326 | 0.76 | HDAC3 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL19063562 | 0.76 | HDAC1 (0.43) | GAARAB9ANPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808440-A1 | Non-covalent inhibitors of urokinase and blood vessel formation | Wilex AG (DE) | 2007-07-18 | — | — | EP | disclosed |
| EP-1182207-B1 | Non-covalent inhibitors of urokinase and blood vessel formation | DENDREON CORP (US) | 2007-04-18 | — | — | EP | disclosed |