Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14471814 | 1.00 | CYP19A1 (0.34) | CYP19A1CYP11B2PDE4APDE4BPDE4C | |
| SCHEMBL14471831 | 1.00 | CYP19A1 (0.34) | CYP19A1CYP11B2PDE4APDE4BPDE4C | |
| SCHEMBL5595601 | 0.83 | TSHR (0.35) | TSHRMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL817341 | 0.83 | TSHR (0.35) | TSHRMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL4442135 | 0.83 | TSHR (0.35) | TSHRMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL23152622 | 0.78 | AKR1C1 (0.41) | CYP19A1CYP11B2TSHRMEN1KMT2A | |
| SCHEMBL11412872 | 0.78 | AKR1C1 (0.41) | CYP19A1CYP11B2TSHRMEN1KMT2A | |
| SCHEMBL11412870 | 0.78 | AKR1C1 (0.41) | CYP19A1CYP11B2TSHRMEN1KMT2A | |
| SCHEMBL817342 | 0.77 | MTNR1A (0.35) | CYP19A1TSHRMEN1KMT2AMTNR1A | |
| SCHEMBL13710705 | 0.77 | AKT1 (0.35) | TSHRAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809567-B2 | Method for producing silylenol ethers | KYOTO UNIVERSITY (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20130053567-A1 | METHOD FOR PRODUCING SILYLENOL ETHERS | KYOTO UNIVERSITY (JP) | 2013-02-28 | — | — | US | disclosed |
| EP-2543674-A1 | METHOD FOR PRODUCING SILYLENOL ETHERS | Kyoto University (JP) | 2013-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053567-A1 | METHOD FOR PRODUCING SILYLENOL ETHERS | AKR7A2, MSMO1, CYP2E1 | CYP19A1 606/4885CYP11B2 85/4885PDE4A 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.