SCHEMBL14472134

SCHEMBL14472134

Cc1c(F)ccc(C(=O)O)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
ALB P02768 1/20 0.42
ADRA2A P08913 1/20 0.41
CLCN2 P51788 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
EPRS1 P07814 1/20 0.41
TSHR P16473 2/20 0.40
NOTUM Q6P988 1/20 0.40
HAAO P46952 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
GABRA2 P47869 1/20 0.39
GABRB2 P47870 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128319 0.85 CYP1A2 (0.58) CYP1A2TSHRNOTUMHAAOGABRP
SCHEMBL31389208 0.85 CYP1A2 (0.58) CYP1A2TSHRNOTUMHAAOGABRP
SCHEMBL1192063 0.84 CES2 (0.45) CYP1A2ALBADRA2ACLCN2CES2
SCHEMBL107175 0.84 CES2 (0.50) CYP1A2ALBADRA2ACLCN2CES2
SCHEMBL29465861 0.84 CES2 (0.50) CYP1A2ALBADRA2ACLCN2CES2
Ammonia Solution, Strong SCHEMBL29137499 0.83 CYP1A2 (0.55) CYP1A2TSHRNOTUMHAAOGABRP
SCHEMBL24718252 0.83 FABP3 (0.41) CYP1A2ALBADRA2ACLCN2CES2
SCHEMBL15285575 0.83 ALB (0.53) CYP1A2ALBADRA2ACLCN2EPRS1
SCHEMBL27295919 0.83 CYP1A2 (0.41) CYP1A2ALBADRA2ACLCN2CES2
SCHEMBL852651 0.81 EPRS1 (0.44) CYP1A2ALBADRA2ACLCN2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119948161-A Chimeric polypeptide systems and methods of gene regulation 安娜萨默尚帕利莫与卡洛斯蒙特斯尚帕利莫基金会-基金会研究中心 2025-05-06 CN disclosed
CN-115715545-A Use of 3-isoxazolidinone compounds as selective herbicides FMC有限公司 2023-02-28 CN disclosed
CN-115669672-A Use of 3-isoxazolidinone compounds as selective herbicides FMC有限公司 2023-02-03 CN disclosed
CN-112741097-B Herbicidal compositions comprising N- (1, 3, 4-oxadiazol-2-yl) arylcarboxamides and their use 江苏清原农冠杂草防治有限公司 2022-11-29 CN disclosed
EP-2222648-B1 PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS ASTRAZENECA AB (SE) 2013-01-09 EP disclosed
CN-101687810-A Bicyclic compound and pharmaceutical use thereof TAKEDA PHARMACEUTICAL 2010-03-31 CN disclosed
CN-100448869-C Anilinopyrazole derivatives for the treatment of diabetes BAYER PHARMACEUTICALS CORP (US) 2009-01-07 CN disclosed
CN-1717401-A Anilinopyrazole derivatives useful for the treatment of diabetes BAYER PHARMACEUTICALS CORP (US) 2006-01-04 CN disclosed
CN-1148385-A 4-benzoylisoxazole derivatives and their use as herbicides RHONE POULENC AGRICULTURE (GB) 1997-04-23 CN disclosed