Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | PPID | Q08752 | 3/20 | 0.42 |
| ▸ | PPIB | P23284 | 2/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | PPIG | Q13427 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15257256 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28568489 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRPLA2G1BATG4BSMN1; SMN2 | |
| SCHEMBL2250967 | 0.78 | EPHX2 (0.51) | EPHX2ITGB1ITGA5ITGA4PPID | |
| Trifluoroacetic Acid SCHEMBL30182377 | 0.71 | ITGB1 (0.53) | EPHX2ITGB1ITGA5ITGA4PPID | |
| Trifluoroacetic Acid SCHEMBL17894376 | 0.71 | ITGB1 (0.53) | EPHX2ITGB1ITGA5ITGA4PPID | |
| SCHEMBL15940349 | 0.70 | ALOX12 (0.65) | ALDH1A1PLA2G1BATG4BSMN1; SMN2 | |
| SCHEMBL258716 | 0.70 | CYP2C9 (0.62) | EPHX2ITGB1ITGA5PPIDPPIB | |
| SCHEMBL15939528 | 0.70 | PPID (0.65) | EPHX2PPIDPPIBPPIAPPIG | |
| SCHEMBL6415716 | 0.69 | EPHX2 (0.50) | EPHX2ITGB1ITGA5PPIDPPIB | |
| SCHEMBL22879077 | 0.69 | EPHX2 (0.41) | EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808440-A1 | Non-covalent inhibitors of urokinase and blood vessel formation | Wilex AG (DE) | 2007-07-18 | — | — | EP | disclosed |