Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 11/20 | 0.35 |
| ▸ | CA2 | P00918 | 11/20 | 0.35 |
| ▸ | CA9 | Q16790 | 11/20 | 0.35 |
| ▸ | CA12 | O43570 | 10/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16234429 | 1.00 | PAX8 (0.41) | PAX8LMNAPRKCAAKT1PTK2 | |
| SCHEMBL16234425 | 0.84 | LMNA (0.38) | LMNAKMT2ATSHR | |
| SCHEMBL14473900 | 0.84 | LMNA (0.38) | LMNAKMT2ATSHR | |
| SCHEMBL16234426 | 0.81 | LMNA (0.40) | PAX8LMNAKMT2ATSHR | |
| SCHEMBL12778793 | 0.79 | CYP2D6 (0.41) | PAX8LMNAPRKCAAKT1PTK2 | |
| SCHEMBL7464539 | 0.78 | LMNA (0.47) | PAX8LMNAPRKCAAKT1PTK2 | |
| SCHEMBL16234461 | 0.77 | PAX8 (0.36) | PAX8LMNAPRKCAAKT1PTK2 | |
| SCHEMBL16273573 | 0.75 | CYP2D6 (0.36) | PAX8PRKCAAKT1PTK2CA1 | |
| SCHEMBL15171149 | 0.75 | TNF (0.35) | PAX8KMT2A | |
| SCHEMBL14817682 | 0.75 | TNF (0.35) | PAX8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013003001-A1 | PROCESS FOR PREPARING HEPARINOIDS AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF | APICORE, LLC (US) | 2013-01-03 | — | — | WO | disclosed |