SCHEMBL14475092

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16183289	0.91	PDE5A (0.43)	PDE5APOLBHPGDKDM4EMAPT
	SCHEMBL14475031	0.91	PDE5A (0.53)	PDE5APOLBGBA1CYP1A2CYP3A4
	SCHEMBL14475219	0.89	PDE5A (0.60)	PDE5APOLBGBA1CYP1A2CYP3A4
	SCHEMBL20273693	0.86	PDE5A (0.54)	PDE5APOLBGBA1CYP1A2CYP3A4
	SCHEMBL16184579	0.84	DYRK1A (0.41)	PDE5APOLBCYP1A2CYP3A4TSHR
	SCHEMBL14727823	0.83	PDE5A (0.62)	PDE5APOLBGBA1CYP1A2CYP3A4
	SCHEMBL14474100	0.82	PDE5A (0.61)	PDE5APOLBGBA1CYP1A2CYP3A4
	SCHEMBL14474908	0.80	PDE5A (0.50)	PDE5APOLBCYP1A2CYP3A4TSHR
	SCHEMBL14475213	0.80	CYP1A2 (0.59)	PDE5APOLBGBA1CYP1A2CYP3A4
	SCHEMBL2155510	0.79	CCNE2 (0.58)	PDE5APOLBGBA1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.