Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.76 |
| ▸ | ACHE | P22303 | 6/20 | 0.76 |
| ▸ | MAPT | P10636 | 6/20 | 0.76 |
| ▸ | RAD52 | P43351 | 5/20 | 0.76 |
| ▸ | KDM1A | O60341 | 5/20 | 0.76 |
| ▸ | EP300 | Q09472 | 5/20 | 0.76 |
| ▸ | LMNA | P02545 | 5/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.67 |
| ▸ | RAC1 | P63000 | 2/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18472034 | 0.93 | ACHE (0.79) | CYP3A4ACHEMAPTRAD52KDM1A | |
| SCHEMBL18472033 | 0.89 | RAC1 (0.74) | CYP3A4ACHEMAPTRAD52KDM1A | |
| SCHEMBL13174366 | 0.87 | CYP3A4 (0.76) | CYP3A4ACHEMAPTRAD52KDM1A | |
| SCHEMBL12641839 | 0.86 | CYP1B1 (0.78) | CYP3A4ACHEMAPTRAD52KDM1A | |
| Palmitine SCHEMBL562120 | 0.86 | CYP3A4 (1.00) | CYP3A4ACHEMAPTRAD52KDM1A | |
| Palmitine SCHEMBL29350054 | 0.86 | CYP3A4 (1.00) | CYP3A4ACHEMAPTRAD52KDM1A | |
| Palmitine SCHEMBL29471136 | 0.86 | CYP3A4 (1.00) | CYP3A4ACHEMAPTRAD52KDM1A | |
| SCHEMBL30138130 | 0.85 | ACHE (0.89) | CYP3A4ACHEMAPTRAD52KDM1A | |
| Palmitine SCHEMBL2445279 | 0.85 | CYP3A4 (0.98) | CYP3A4ACHEMAPTRAD52KDM1A | |
| Palmitine SCHEMBL29766942 | 0.85 | CYP3A4 (1.00) | CYP3A4ACHEMAPTRAD52KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695193-B2 | Inhibitors of Plasmodium falciparum equilibrative nucleoside transporter type I as anti-parasitic compounds | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-07-04 | — | — | US | disclosed |
| US-9341605-B2 | Chemical profile of detecting bioactive components of quinones, stilbenes, flavones and alkaloids | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2016-05-17 | — | — | US | disclosed |
| US-20160122362-A1 | INHIBITORS OF PLASMODIUM FALCIPARUM EQUILIBRATIVE NUCLEOSIDE TRANSPORTER TYPE I AS ANTI-PARASITIC COMPOUNDS | UNIV COLUMBIA (US) | 2016-05-05 | — | — | US | disclosed |
| US-20130000389-A1 | CHEMICAL PROFILE OF DETECTING BIOACTIVE COMPONENTS OF QUINONES, STILBENES, FLAVONES AND ALKALOIDS | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122362-A1 | INHIBITORS OF PLASMODIUM FALCIPARUM EQUILIBRATIVE NUCLEOSIDE TRANSPORTER TYPE I AS ANTI-PARASITIC COMPOUNDS | SLC29A1, SLC29A2, SLC28A1 | CYP3A4 1178/4885ACHE 3634/4885MAPT 2408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.