Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14477647 | 0.96 | CYP2D6 (0.40) | CYP2D6TP53CYP1A2CYP3A4ALOX12 | |
| SCHEMBL14477643 | 0.90 | GRIN1 (0.37) | GRIN1GRIN2AGRIN2BSIGMAR1OPRD1 | |
| SCHEMBL14312096 | 0.90 | CYP2D6 (0.49) | CYP2D6TP53CYP1A2CYP3A4ALOX12 | |
| Tetraxetan SCHEMBL8907977 | 0.89 | CYP2D6 (0.48) | CYP2D6TP53CYP1A2CYP3A4ALOX12 | |
| SCHEMBL14477642 | 0.86 | CXCR4 (0.41) | GRIN1GRIN2AGRIN2BSIGMAR1OPRD1 | |
| SCHEMBL14312072 | 0.85 | CYP2D6 (0.46) | CYP2D6TP53CYP1A2CYP3A4ALOX12 | |
| SCHEMBL14327160 | 0.85 | CYP2D6 (0.50) | CYP2D6TP53CYP1A2CYP3A4ALOX12 | |
| SCHEMBL14477671 | 0.84 | SIGMAR1 (0.43) | CYP2D6CYP1A2CYP3A4KCNH2KCNJ1 | |
| SCHEMBL14478355 | 0.84 | CYP2D6 (0.46) | CYP2D6TP53CYP1A2CYP3A4ALOX12 | |
| SCHEMBL8654441 | 0.84 | CYP2D6 (0.54) | CYP2D6TP53CYP1A2CYP3A4ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079867-B2 | Polyazamacrocyclic compound, and a production method and a biomedical use therefor | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2015-07-14 | — | — | US | disclosed |
| US-20130004423-A1 | POLYAZAMACROCYCLIC COMPOUND, AND A PRODUCTION METHOD AND A BIOMEDICAL USE THEREFOR | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004423-A1 | POLYAZAMACROCYCLIC COMPOUND, AND A PRODUCTION METHOD AND A BIOMEDICAL USE THEREFOR | SLC39A11, VIP, PBDC1 | CYP2D6 4235/4885TP53 2040/4885CYP1A2 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.