Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14477642 | 0.95 | CXCR4 (0.41) | GRIN1GRIN2AGRIN2BSIGMAR1CXCR4 | |
| SCHEMBL14477644 | 0.90 | CYP2D6 (0.42) | GRIN1GRIN2AGRIN2BSIGMAR1OPRD1 | |
| SCHEMBL14312212 | 0.90 | SIGMAR1 (0.46) | GRIN1GRIN2AGRIN2BSIGMAR1CXCR4 | |
| SCHEMBL14477647 | 0.86 | CYP2D6 (0.40) | GRIN1GRIN2AGRIN2BSIGMAR1CXCR4 | |
| SCHEMBL14312255 | 0.85 | CXCR4 (0.50) | GRIN1GRIN2AGRIN2BSIGMAR1CXCR4 | |
| SCHEMBL14477665 | 0.83 | SIGMAR1 (0.42) | SIGMAR1CXCR4CHRM1MEN1CHRM2 | |
| SCHEMBL8038145 | 0.83 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2BCHRM1HRH3 | |
| SCHEMBL16656265 | 0.83 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2BCHRM1HRH3 | |
| SCHEMBL12018087 | 0.80 | GRIN1 (0.47) | GRIN1GRIN2AGRIN2BCHRM1OPRD1 | |
| SCHEMBL14477657 | 0.79 | CXCR4 (0.56) | CXCR4CHRM1MEN1CHRM2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079867-B2 | Polyazamacrocyclic compound, and a production method and a biomedical use therefor | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2015-07-14 | — | — | US | disclosed |
| US-20130004423-A1 | POLYAZAMACROCYCLIC COMPOUND, AND A PRODUCTION METHOD AND A BIOMEDICAL USE THEREFOR | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004423-A1 | POLYAZAMACROCYCLIC COMPOUND, AND A PRODUCTION METHOD AND A BIOMEDICAL USE THEREFOR | SLC39A11, VIP, PBDC1 | GRIN1 3533/4885GRIN2A 4294/4885GRIN2B 3659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.