Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APC | P25054 | 3/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.49 |
| ▸ | QRFPR | Q96P65 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478103 | 0.95 | APC (0.60) | APC | |
| SCHEMBL14478105 | 0.85 | OPRD1 (0.57) | APC | |
| SCHEMBL14478152 | 0.84 | APC (0.51) | APCMMENAALAD2 | |
| SCHEMBL31031528 | 0.84 | NAALAD2 (0.55) | NAALAD2 | |
| SCHEMBL14478026 | 0.84 | LCK (0.53) | APCKEAP1PTPN1MMP1 | |
| SCHEMBL14478087 | 0.83 | APC (0.43) | APCKEAP1QRFPRPTPN1MME | |
| SCHEMBL14478093 | 0.83 | APC (0.44) | APCKEAP1QRFPRMME | |
| SCHEMBL3634638 | 0.82 | OPRD1 (0.51) | APCNAALAD2MMP1 | |
| SCHEMBL2735762 | 0.82 | APC (0.52) | APCKEAP1QRFPRPTPN1MMP1 | |
| SCHEMBL26464896 | 0.81 | KEAP1 (0.53) | KEAP1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013001297-A1 | BINDING INHIBITORS OF THE BETA.TRANSDUCIN REPEAT - CONTAINING PROTEIN | ITI SCOTLAND LIMITED (GB) | 2013-01-03 | — | — | WO | disclosed |