Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.58 |
| ▸ | MGLL | Q99685 | 14/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14000501 | 0.86 | DDAH1 (0.61) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL19480442 | 0.85 | DDAH1 (0.56) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL17231644 | 0.81 | HPGD (0.58) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL20750037 | 0.81 | DDAH1 (0.51) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL10968265 | 0.80 | DDAH1 (0.63) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL11791404 | 0.79 | ALDH1A1 (0.61) | TDP1ALDH1A1HPGDHTTHDAC1 | |
| SCHEMBL17208725 | 0.79 | DDAH1 (0.53) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL17208726 | 0.79 | HTT (0.55) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL3339259 | 0.79 | DDAH1 (0.61) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL22520781 | 0.78 | DDAH1 (0.56) | DDAH1MGLLHSP90AA1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315699-B1 | HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS | SOLULINK INC (US) | 2013-01-02 | — | — | EP | disclosed |