Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12026106 | 0.80 | MIF (0.33) | ALDH1A1TSHRCYP3A4NOS3NOS1 | |
| SCHEMBL24385153 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL18533548 | 0.72 | TSHR (0.54) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL234461 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL21841396 | 0.70 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL13711472 | 0.70 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL27473140 | 0.70 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL14294476 | 0.70 | HDAC3 (0.41) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL11296929 | 0.69 | HRH3 (0.50) | MAPTNOS3NOS1NOS2 | |
| SCHEMBL12134592 | 0.69 | CA1 (0.43) | ALDH1A1HSD17B10TSHRTP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130004427-A1 | TARGETED DENDRIMER-DRUG CONJUGATES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004427-A1 | TARGETED DENDRIMER-DRUG CONJUGATES | FOLH1, DNPEP, PIGO | ALDH1A1 159/4885HSD17B10 565/4885TSHR 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.