Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890213 | 1.00 | OPRM1 (0.53) | OPRM1OPRK1OPRL1LMNAALDH1A1 | |
| SCHEMBL303920 | 0.89 | LMNA (0.63) | OPRM1OPRK1OPRL1LMNAALDH1A1 | |
| SCHEMBL2707046 | 0.89 | LMNA (0.63) | OPRM1OPRK1OPRL1LMNAALDH1A1 | |
| SCHEMBL13748125 | 0.86 | OPRM1 (0.52) | OPRM1OPRK1OPRL1LMNAALDH1A1 | |
| SCHEMBL14478021 | 0.85 | OPRM1 (0.51) | OPRM1OPRK1OPRL1LMNAALDH1A1 | |
| SCHEMBL888780 | 0.85 | OPRM1 (0.51) | OPRM1OPRK1OPRL1LMNAALDH1A1 | |
| SCHEMBL13160613 | 0.84 | OPRM1 (0.50) | OPRM1OPRK1OPRL1LMNAALDH1A1 | |
| SCHEMBL8910357 | 0.84 | OPRM1 (0.50) | OPRM1OPRK1OPRL1LMNAALDH1A1 | |
| SCHEMBL8917644 | 0.84 | OPRM1 (0.50) | OPRM1OPRK1OPRL1LMNAALDH1A1 | |
| SCHEMBL10076713 | 0.82 | LMNA (0.71) | LMNAALDH1A1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8574563-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-11-05 | — | — | US | disclosed |
| US-20130004457-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004457-A1 | Hepatitis C Virus Inhibitors | HAVCR2, PYGL, HCCS | OPRM1 2169/4885OPRK1 1789/4885OPRL1 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.