Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2088495 | 0.75 | TSHR (0.42) | MAPT | |
| SCHEMBL7054960 | 0.71 | — | — | |
| SCHEMBL1507066 | 0.71 | — | — | |
| SCHEMBL17527809 | 0.71 | CHRNB2 (0.43) | CHRNB2CHRNA4MAPTKMT2A | |
| SCHEMBL27919624 | 0.71 | CHRNB2 (0.43) | CHRNB2CHRNA4MAPTKMT2A | |
| SCHEMBL14480055 | 0.70 | — | — | |
| SCHEMBL3050102 | 0.70 | CHRNB2 (0.70) | CHRNB2CHRNA4 | |
| SCHEMBL875081 | 0.70 | CHRNB2 (0.46) | CHRNB2CHRNA4MAPTKMT2A | |
| SCHEMBL486311 | 0.69 | MAPT (0.55) | MAPTKMT2A | |
| SCHEMBL12086547 | 0.68 | CHRNB2 (0.44) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2719688-B1 | Process for producing tetrazolyloxime derivatives | NIPPON SODA CO (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2719686-B1 | Process to halogenate a picoline derivative | NIPPON SODA CO (JP) | 2015-12-02 | — | — | EP | disclosed |
| EP-2719687-B1 | Process to make a bromopicoline derivative | NIPPON SODA CO (JP) | 2015-09-16 | — | — | EP | disclosed |
| US-9018385-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| US-9012653-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9000178-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-8962848-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2015-02-24 | — | — | US | disclosed |
| US-8841458-B2 | Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative | NIPPON SODA CO., LTD. (JP) | 2014-09-23 | — | — | US | disclosed |
| US-20140155612-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140155611-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140155613-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140155615-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2719688-A1 | Process for producing tetrazolyloxime derivatives | NIPPON SODA CO., LTD. (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2719687-A1 | Process to make a bromopicoline derivative | NIPPON SODA CO., LTD. (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2719686-A1 | Process to halogenate a picoline derivative | NIPPON SODA CO., LTD. (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2546236-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | Nippon Soda Co., Ltd. (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-20130012713-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | NIPPON SODA CO., LTD | 2013-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155615-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | CBR3, PNPO, AADAC | CHRNB2 3542/4885CHRNA4 2351/4885MAPT 4042/4885 |
| US-20140155612-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | CBR3, PNPO, AADAC | CHRNB2 3542/4885CHRNA4 2351/4885MAPT 4042/4885 |
| US-20140155611-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | CBR3, PNPO, AADAC | CHRNB2 3542/4885CHRNA4 2351/4885MAPT 4042/4885 |
| US-20140155613-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | CBR3, PNPO, AADAC | CHRNB2 3542/4885CHRNA4 2351/4885MAPT 4042/4885 |
| US-20130012713-A1 | COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE | CBR3, PNPO, AADAC | CHRNB2 3542/4885CHRNA4 2351/4885MAPT 4042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.