SCHEMBL14480792

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21780397	0.85	AR (0.43)	ROCK2ROCK1HRH3KCNH2HTR2A
	SCHEMBL14481095	0.85	AR (0.43)	ROCK2ROCK1HRH3KCNH2HTR2A
	SCHEMBL14480619	0.85	AR (0.43)	ROCK2ROCK1HRH3KCNH2HTR2A
	SCHEMBL21780418	0.83	HTR2A (0.41)	ROCK2ROCK1HRH3KCNH2HTR2A
	SCHEMBL21780475	0.83	HTR2C (0.55)	HTR2AHTR2CHTR2B
	SCHEMBL14481143	0.83	HTR2C (0.55)	HTR2AHTR2CHTR2B
	SCHEMBL14481562	0.83	HTR2C (0.55)	HTR2AHTR2CHTR2B
	SCHEMBL21780490	0.80	HRH3 (0.37)	ROCK2ROCK1HRH3KCNH2HTR2A
	SCHEMBL14480767	0.80	HRH3 (0.37)	ROCK2ROCK1HRH3KCNH2HTR2A
	SCHEMBL14480898	0.80	HRH3 (0.37)	ROCK2ROCK1HRH3KCNH2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.