Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017690 | 0.81 | MCL1 (0.44) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14017682 | 0.78 | KMT2A (0.46) | SMN1; SMN2ALDH1A1POLBMAPTGAA | |
| SCHEMBL14486187 | 0.73 | MTNR1A (0.39) | MTNR1AMTNR1BALDH1A1POLBMAPT | |
| SCHEMBL10397769 | 0.73 | AKR1C3 (0.50) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10397770 | 0.73 | AKR1C3 (0.50) | MTNR1AMTNR1BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14486009 | 0.72 | KDM4E (0.40) | MTNR1AMTNR1BALDH1A1POLBMAPT | |
| SCHEMBL902680 | 0.72 | GAA (0.61) | RAB9ASMN1; SMN2NPC1ALDH1A1POLB | |
| SCHEMBL14488786 | 0.71 | CES1 (0.53) | MTNR1AMTNR1BRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10397669 | 0.71 | PTAFR (0.69) | PTAFR | |
| SCHEMBL10397667 | 0.71 | PTAFR (0.69) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229609-B2 | Diarylbutadiene-substituted methyltrialkylsilanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2007-06-12 | — | — | US | disclosed |