Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.53 |
| ▸ | CES2 | O00748 | 6/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397770 | 0.81 | AKR1C3 (0.50) | CES1CES2MTNR1AMTNR1BMAPT | |
| SCHEMBL10397769 | 0.81 | AKR1C3 (0.50) | CES1CES2MTNR1AMTNR1BMAPT | |
| SCHEMBL10399172 | 0.78 | ALDH1A1 (0.51) | MTNR1AMTNR1BMAPTALDH1A1KDM4E | |
| SCHEMBL10399175 | 0.78 | ALDH1A1 (0.51) | MTNR1AMTNR1BMAPTALDH1A1KDM4E | |
| Bicarbonate SCHEMBL9520975 | 0.75 | MTNR1A (0.47) | CES1CES2MTNR1AMTNR1BMAPT | |
| SCHEMBL11040010 | 0.74 | GAA (0.50) | CES1CES2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11040015 | 0.74 | GAA (0.50) | CES1CES2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL88322 | 0.73 | ALDH1A1 (0.46) | CES1CES2MTNR1AMTNR1BMAPT | |
| SCHEMBL9520971 | 0.73 | MTNR1A (0.50) | CES1CES2MTNR1AMTNR1BMAPT | |
| SCHEMBL27932119 | 0.73 | MTNR1A (0.42) | CES1CES2MTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229610-B2 | Diarylbutadiene-substituted diorganopolysiloxanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2007-06-12 | — | — | US | disclosed |