SCHEMBL14487377

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15708370	0.89	TRPM2 (0.41)	TRPM2MAPK1TSHRCNR1LMNA
	SCHEMBL31395465	0.81	TRPM2 (0.42)	TRPM2MAPK1TSHRLMNAPOLB
	SCHEMBL14487581	0.81	TRPM2 (0.42)	TRPM2MAPK1TSHRLMNAPOLB
	SCHEMBL16006668	0.81	TRPM2 (0.36)	TRPM2MAPK1TSHRKMT2APOLB
	SCHEMBL14487510	0.79	PTGS2 (0.40)	TRPM2MAPK1TSHRCNR1POLB
	SCHEMBL14555698	0.77	TRPM2 (0.42)	TRPM2MAPK1TSHRPOLBGAA
	SCHEMBL20371748	0.77	POLB (0.40)	TRPM2MAPK1TSHRKMT2APOLB
	SCHEMBL14487355	0.77	POLB (0.40)	TRPM2MAPK1TSHRKMT2APOLB
	SCHEMBL21420062	0.76	TRPM2 (0.37)	TRPM2MAPK1TSHRKMT2APOLB
	SCHEMBL21420071	0.76	TRPM2 (0.37)	TRPM2MAPK1TSHRKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.