SCHEMBL14488147

SCHEMBL14488147

CCC1CN(CC)CCN(CC)CCN(CC)CCN1CC

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.35
TMEM97 Q5BJF2 2/20 0.35
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HSD11B1 P28845 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CHRNA7 P36544 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9801352 0.98 SIGMAR1 (0.36) SIGMAR1TMEM97ALDH1A1KDM4E
SCHEMBL9801669 0.83 SIGMAR1 (0.35) SIGMAR1
SCHEMBL7984593 0.81 SIGMAR1 (0.40) SIGMAR1TMEM97ALDH1A1KDM4E
SCHEMBL7380009 0.81 SIGMAR1 (0.35) SIGMAR1TMEM97ALDH1A1KDM4E
SCHEMBL9801964 0.80 SIGMAR1 (0.40) SIGMAR1TMEM97ALDH1A1KDM4E
SCHEMBL9801178 0.80 ALOX15 (0.43) SIGMAR1
SCHEMBL16576610 0.80 SLC18A2 (0.36) SIGMAR1TMEM97ALDH1A1KDM4E
SCHEMBL9870178 0.79 SIGMAR1 (0.33) SIGMAR1ALDH1A1KDM4E
SCHEMBL9801615 0.77 SIGMAR1 (0.44) SIGMAR1TMEM97ALDH1A1
SCHEMBL9801645 0.77 FNTA (0.32) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7226578-B2 Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis SHERING AG (DE) 2007-06-05 US disclosed