Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | THRA | P10827 | 3/20 | 0.44 |
| ▸ | PCNA | P12004 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 2/20 | 0.39 |
| ▸ | PNLIP | P16233 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124417 | 0.83 | PCNA (0.63) | THRBTHRAPCNAALOX15SMN1; SMN2 | |
| SCHEMBL14553380 | 0.78 | THRB (0.52) | THRBTHRAPCNAHDAC3EGFR | |
| SCHEMBL16124464 | 0.76 | PCNA (0.53) | THRBTHRAPCNAFADS1ALOX15 | |
| SCHEMBL16126154 | 0.72 | ALOX15 (0.46) | PCNAHDAC3EGFRHDAC4HDAC1 | |
| SCHEMBL16124418 | 0.72 | PCNA (0.63) | THRBTHRAPCNASMN1; SMN2LMNA | |
| SCHEMBL16124445 | 0.70 | PCNA (0.56) | THRBTHRAPCNAHDAC3EGFR | |
| SCHEMBL16124502 | 0.70 | THRB (0.66) | THRBTHRAPCNATMPRSS4PNLIP | |
| SCHEMBL16124435 | 0.65 | PCNA (0.69) | PCNALMNA | |
| SCHEMBL16124463 | 0.65 | PCNA (0.53) | THRBTHRAPCNAALDH1A1 | |
| SCHEMBL7197436 | 0.63 | TMPRSS4 (0.67) | HDAC3EGFRHDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006734-A1 | SUBSTITUTED 4-PHENOXYPHENOL ANALOGS AS MODULATORS OF PROLIFERATING CELL NUCLEAR ANTIGEN ACTIVITY | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2013-01-10 | — | — | WO | disclosed |