Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 12/20 | 0.52 |
| ▸ | THRA | P10827 | 10/20 | 0.52 |
| ▸ | PCNA | P12004 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124417 | 0.90 | PCNA (0.63) | THRBTHRAPCNAALOX15LMNA | |
| SCHEMBL16124464 | 0.84 | PCNA (0.53) | THRBTHRAPCNAALOX15LMNA | |
| SCHEMBL16124418 | 0.79 | PCNA (0.63) | THRBTHRAPCNALMNA | |
| SCHEMBL14488333 | 0.78 | THRB (0.44) | THRBTHRAPCNAALOX15LMNA | |
| SCHEMBL16124502 | 0.77 | THRB (0.66) | THRBTHRAPCNALMNA | |
| SCHEMBL16124445 | 0.77 | PCNA (0.56) | THRBTHRAPCNAALOX15LMNA | |
| SCHEMBL16126154 | 0.76 | ALOX15 (0.46) | PCNAALOX15LMNAHDAC3EGFR | |
| SCHEMBL14553372 | 0.75 | THRB (0.53) | THRBTHRAPCNA | |
| SCHEMBL16124463 | 0.73 | PCNA (0.53) | THRBTHRAPCNA | |
| SCHEMBL2786630 | 0.69 | THRB (1.00) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006734-A1 | SUBSTITUTED 4-PHENOXYPHENOL ANALOGS AS MODULATORS OF PROLIFERATING CELL NUCLEAR ANTIGEN ACTIVITY | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2013-01-10 | — | — | WO | disclosed |