Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 7/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1449804 | 0.92 | UBE2M (0.51) | UBE2MDCUN1D1TP53LMNATHRB | |
| Hydrochloric Acid SCHEMBL1449029 | 0.91 | UBE2M (0.50) | UBE2MDCUN1D1TP53LMNATHRB | |
| Hydrochloric Acid SCHEMBL1450097 | 0.90 | UBE2M (0.56) | UBE2MDCUN1D1TP53LMNATHRB | |
| Hydrochloric Acid SCHEMBL1448969 | 0.89 | TP53 (0.54) | UBE2MDCUN1D1TP53LMNATHRB | |
| Hydrochloric Acid SCHEMBL2571561 | 0.89 | UBE2M (0.61) | UBE2MDCUN1D1TP53LMNATHRB | |
| Hydrochloric Acid SCHEMBL1450078 | 0.88 | UBE2M (0.55) | UBE2MDCUN1D1TP53LMNATHRB | |
| Hydrochloric Acid SCHEMBL1448892 | 0.88 | UBE2M (0.57) | UBE2MDCUN1D1TP53LMNATHRB | |
| Hydrochloric Acid SCHEMBL1449286 | 0.88 | TP53 (0.47) | UBE2MDCUN1D1TP53LMNATHRB | |
| Hydrochloric Acid SCHEMBL1449122 | 0.87 | UBE2M (0.51) | UBE2MDCUN1D1TP53LMNATHRB | |
| Hydrochloric Acid SCHEMBL1449144 | 0.87 | UBE2M (0.53) | UBE2MDCUN1D1TP53LMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385040-A1 | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO Pharmaceutical Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7910741-B2 | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20060178399-A1 | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-08-10 | — | — | US | disclosed |
| EP-1604981-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178399-A1 | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient | HLA-DRB1, ELANE, MMP8 | UBE2M 3256/4885DCUN1D1 3114/4885TP53 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.