Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14489255 | 0.83 | THRB (0.51) | THRBTHRA | |
| SCHEMBL5397866 | 0.83 | THRB (0.69) | THRBTHRA | |
| SCHEMBL14488902 | 0.82 | THRB (0.70) | THRBTHRA | |
| SCHEMBL14489180 | 0.82 | THRB (0.51) | THRBTHRA | |
| SCHEMBL14488964 | 0.80 | THRB (0.62) | THRBTHRA | |
| SCHEMBL5408047 | 0.78 | THRA (1.00) | THRBTHRA | |
| SCHEMBL14488999 | 0.78 | THRB (0.50) | THRBTHRA | |
| SCHEMBL14489241 | 0.78 | THRB (0.51) | THRBTHRA | |
| SCHEMBL14489239 | 0.78 | THRB (0.53) | THRBTHRA | |
| SCHEMBL6852992 | 0.77 | THRA (0.57) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230031-B2 | Thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-06-12 | — | — | US | disclosed |