SCHEMBL14489334

SCHEMBL14489334

CCC(C)OCNC(=O)C(C)(C)CC

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 4/20 0.40
DRD2 P14416 2/20 0.33
DRD4 P21917 2/20 0.33
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14489342 0.81
SCHEMBL14499780 0.79
SCHEMBL23945672 0.76 FAAH (0.40) RIPK1DRD2DRD4
SCHEMBL17717734 0.75 RIPK1 (0.40) RIPK1DRD2DRD4MMP8
SCHEMBL19821916 0.75 MTNR1A (0.37)
SCHEMBL12404486 0.75 RIPK1 (0.46) RIPK1DRD2DRD4
SCHEMBL13568036 0.73 RIPK1 (0.44) RIPK1DRD2DRD4MMP8
SCHEMBL19822018 0.72 HSD17B10 (0.31)
SCHEMBL27051359 0.71 RIPK1 (0.40) RIPK1DRD2DRD4MMP8
SCHEMBL13063228 0.71 CYP2D6 (0.48) RIPK1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7235342-B2 Negative photoresist composition including non-crosslinking chemistry INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-06-26 US disclosed