SCHEMBL1448988

SCHEMBL1448988

Brc1ccc(-c2nc3ccccc3s2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.69
APP P05067 7/20 0.69
NPC1 O15118 7/20 0.69
KDM4E B2RXH2 4/20 0.69
MAPT P10636 3/20 0.69
GLA P06280 2/20 0.69
GAA P10253 2/20 0.69
MMP9 P14780 2/20 0.69
MMP8 P22894 2/20 0.69
ALDH1A1 P00352 2/20 0.69
LMNA P02545 1/20 0.69
SMN1; SMN2 Q16637 3/20 0.63
KMT2A Q03164 3/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
MEN1 O00255 2/20 0.63
PKM P14618 2/20 0.63
PAX8 Q06710 1/20 0.63
NOD2 Q9HC29 1/20 0.63
TNF P01375 1/20 0.63
NOD1 Q9Y239 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28961169 0.98 RAB9A (0.67) RAB9AAPPNPC1KDM4EMAPT
Hydrochloric Acid SCHEMBL28612083 0.98 RAB9A (0.67) RAB9AAPPNPC1KDM4EMAPT
SCHEMBL30396579 0.98 RAB9A (0.67) RAB9AAPPNPC1KDM4EMAPT
SCHEMBL366824 0.90 RAB9A (0.81) RAB9AAPPNPC1KDM4EMAPT
SCHEMBL29474819 0.90 RAB9A (0.81) RAB9AAPPNPC1KDM4EMAPT
SCHEMBL24295138 0.88 RAB9A (0.79) RAB9AAPPNPC1KDM4EMAPT
SCHEMBL754574 0.85 RAB9A (0.73) RAB9AAPPNPC1KDM4EMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL30988131 0.84 RAB9A (0.75) RAB9AAPPNPC1KDM4EMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL94005 0.84 RAB9A (0.75) RAB9AAPPNPC1KDM4EMAPT
SCHEMBL21313421 0.84 KDM4E (0.59) RAB9AAPPNPC1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118725333-A Keggin type polyacid-based metal organic framework molecular material, synthesis method and application of Keggin type polyacid-based metal organic framework molecular material as photocatalyst 周口师范学院 2024-10-01 CN claimed
CN-117286499-A Copper etching solution 福建钰融科技有限公司 2023-12-26 CN claimed
CN-116284058-A Sulfur-nitrogen accurate co-doped graphite alkyne and preparation method thereof 青岛科技大学 2023-06-23 CN claimed
CN-110358059-B Preparation method of POSS-containing phosphorescent polymer material 福建师范大学 2021-08-06 CN claimed
US-10655015-B2 Tire crumb-based bitumen polymer for producing a lower viscosity asphalt with improved tolerance to high temperatures Argopro Group LLC (US) 2020-05-19 US claimed
US-20200095424-A1 TIRE CRUMB-BASED BITUMEN POLYMER FOR PRODUCING A LOWER VISCOSITY ASPHALT WITH IMPROVED TOLERANCE TO HIGH TEMPERATURES Argopro Group LLC 2020-03-26 US claimed
CN-110358059-A A kind of preparation method of the phosphorescent polymer material containing POSS 福建师范大学 2019-10-22 CN claimed
CN-104761536-B Method of synthesizing 2-substituted benzothiazole-type derivative 内蒙古工业大学 2017-05-10 CN claimed
CN-103265539-B For distinguishing fluorescent probe benzothiazole-terpyridyl compounds and the methods for making and using same thereof of detection zine ion and cadmium ion ZHEJIANG UNIVERSITY (CN) 2015-09-02 CN claimed
CN-104761536-A Method of synthesizing 2-substituted benzothiazole-type derivative UNIV INNER MONGOLIA TECHNOLOGY 2015-07-08 CN claimed
CN-103214428-B Benzothiazole-cyanophenyl compound serving as hydrazine fluorescence probe as well as preparation method and application method of benzothiazole-cyanophenyl compound UNIV ZHEJIANG 2014-11-26 CN claimed
CN-102942537-B Benzothiazole-aniline compound used as pH fluorescent probe and preparation method thereof UNIV ZHEJIANG 2014-07-02 CN claimed
CN-103265539-A Fluorescent probe: benzothiazole-terpyridine compound used for distinguishing and detecting zinc ions and cadmium ions, preparation method and application method thereof UNIV ZHEJIANG 2013-08-28 CN claimed
CN-103214428-A Benzothiazole-cyanophenyl compound serving as hydrazine fluorescence probe as well as preparation method and application method of benzothiazole-cyanophenyl compound UNIV ZHEJIANG 2013-07-24 CN claimed
CN-102942537-A Benzothiazole-aniline compound used as pH fluorescent probe and preparation method thereof UNIV ZHEJIANG 2013-02-27 CN claimed
US-20260084134-A1 STORAGE AND DELIVERY OF GASEOUS CHEMICAL REACTANTS IN CHEMICAL PROCESSES USING METAL-ORGANIC FRAMEWORKS UNIV CORNELL (US) 2026-03-26 US disclosed
EP-4131456-B1 ORGANIC LIGHT-EMITTING DEVICE SFC CO LTD (KR) 2026-02-18 EP disclosed
EP-0674635-A1 QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS ZENECA LIMITED (GB) 1995-10-04 EP disclosed
WO-1994014803-A1 QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS ZENECA LIMITED (GB) 1994-07-07 WO disclosed
US-4892953-A Benzthiazole substituted diacid terphenyl monomers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1990-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260084134-A1 STORAGE AND DELIVERY OF GASEOUS CHEMICAL REACTANTS IN CHEMICAL PROCESSES USING METAL-ORGANIC FRAMEWORKS ME3, ME2, SLC25A11 RAB9A 3129/4885APP 2246/4885NPC1 545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.