Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13957035 | 0.88 | CYP19A1 (0.86) | CYP19A1HDAC6HDAC1HDAC10P2RX4 | |
| SCHEMBL10977143 | 0.85 | CYP19A1 (0.64) | CYP19A1HDAC6HDAC1HDAC10P2RX4 | |
| SCHEMBL10977145 | 0.85 | CYP19A1 (0.64) | CYP19A1HDAC6HDAC1HDAC10P2RX4 | |
| SCHEMBL29405472 | 0.85 | CYP19A1 (0.63) | CYP19A1HDAC6HDAC1HDAC10P2RX4 | |
| SCHEMBL955942 | 0.85 | CYP19A1 (0.63) | CYP19A1HDAC6HDAC1HDAC10P2RX4 | |
| SCHEMBL30681661 | 0.85 | CYP19A1 (0.63) | CYP19A1HDAC6HDAC1HDAC10P2RX4 | |
| SCHEMBL30007452 | 0.81 | CYP19A1 (1.00) | CYP19A1HDAC6HDAC1HDAC10P2RX4 | |
| SCHEMBL151053 | 0.81 | CYP19A1 (1.00) | CYP19A1HDAC6HDAC1HDAC10P2RX4 | |
| SCHEMBL29093702 | 0.80 | CYP19A1 (0.73) | CYP19A1HDAC6HDAC1HDAC10P2RX4 | |
| SCHEMBL17841725 | 0.80 | CYP19A1 (0.73) | CYP19A1HDAC6HDAC1HDAC10P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7227027-B2 | Carbazole derivative and its use in electroluminescent devices | TSINGHUA UNIVERSITY (CH) | 2007-06-05 | — | — | US | disclosed |
| US-7227027-B2 | Carbazole derivative and its use in electroluminescent devices | TSINGHUA UNIVERSITY (CH) | 2007-06-05 | — | — | US | disclosed |