SCHEMBL955942

SCHEMBL955942

C=Cc1ccc(Cn2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 1/20 0.63
▸ LMNA P02545 2/20 0.62
▸ PSMD14 O00487 1/20 0.62
▸ P2RX4 Q99571 4/20 0.51
▸ HDAC6 Q9UBN7 3/20 0.50
▸ HDAC1 Q13547 1/20 0.50
▸ HDAC10 Q969S8 1/20 0.50
▸ CA1 P00915 3/20 0.46
▸ CA2 P00918 3/20 0.46
▸ CYP1A2 P05177 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ HDAC3 O15379 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ USP2 O75604 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30681661 1.00 CYP19A1 (0.63) CYP19A1LMNAPSMD14P2RX4HDAC6
SCHEMBL29405472 1.00 CYP19A1 (0.63) CYP19A1LMNAPSMD14P2RX4HDAC6
SCHEMBL1223439 0.90 P2RX4 (0.68) CYP19A1LMNAPSMD14P2RX4HDAC6
SCHEMBL17457937 0.89 PSMD14 (0.53) CYP19A1LMNAPSMD14P2RX4HDAC6
SCHEMBL16627135 0.87 PSMD14 (0.51) CYP19A1LMNAPSMD14P2RX4HDAC6
SCHEMBL31165289 0.87 PSMD14 (0.51) CYP19A1LMNAPSMD14P2RX4HDAC6
SCHEMBL10064304 0.86 PSMD14 (0.50) CYP19A1LMNAPSMD14P2RX4HDAC6
SCHEMBL14492838 0.85 CYP19A1 (0.68) CYP19A1LMNAPSMD14P2RX4HDAC6
SCHEMBL13957035 0.84 CYP19A1 (0.86) CYP19A1P2RX4HDAC6HDAC1HDAC10
SCHEMBL18638857 0.84 HDAC6 (0.51) CYP19A1LMNAPSMD14HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117323824-A Method for preparing hydrogen-resistant negative film by roller type gum dipping method 山东天维膜技术有限公司 2024-01-02 — — CN claimed
US-10961383-B2 Gradient block copolymers for directed self-assembly BREWER SCIENCE, INC. (US) 2021-03-30 — — US claimed
CN-110470717-A A kind of preparation method of the screen printing electrode of composite nano materials modification UNIV JIANGNAN 2019-11-19 — — CN claimed
WO-2019152078-A1 GRADIENT BLOCK COPOLYMERS FOR DIRECTED SELF-ASSEMBLY BREWER SCIENCE, INC. (US) 2019-08-08 — — WO claimed
US-20190233636-A1 GRADIENT BLOCK COPOLYMERS FOR DIRECTED SELF-ASSEMBLY BREWER SCIENCE, INC. 2019-08-01 — — US claimed
CN-104650288-A Preparation method and application of amphiphilic photoelectric active branched macromolecules UNIV JIANGNAN 2015-05-27 — — CN claimed
CN-101619124-B Comb-shaped polymer containing carbazole lateral chain and preparation method thereof UNIV SUZHOU 2011-04-20 — — CN claimed
CN-101619124-A Comb-shaped polymer containing carbazole lateral chain and preparation method thereof UNIV SUZHOU 2010-01-06 — — CN claimed
CN-117323824-A Method for preparing hydrogen-resistant negative film by roller type gum dipping method 山东天维膜技术有限公司 2024-01-02 — — CN disclosed
US-20230329080-A1 THERMALLY-CROSSLINKABLE LOW MOLECULAR WEIGHT COMPOUND-CONTAINING COMPOSITION FOR LIGHT EMITTING DIODE HODOGAYA CHEMICAL CO., LTD. (JP) 2023-10-12 — — US disclosed
CN-110511607-B Printing ink and preparation method and application thereof TCL科技集团股份有限公司 2021-12-31 — — CN disclosed
CN-110511614-B Printing ink and preparation method and application thereof TCL科技集团股份有限公司 2021-12-31 — — CN disclosed
US-10961383-B2 Gradient block copolymers for directed self-assembly BREWER SCIENCE, INC. (US) 2021-03-30 — — US disclosed
US-10734239-B2 High-chi block copolymers with tunable glass transition temperatures for directed self-assembly BREWER SCIENCE, INC. (US) 2020-08-04 — — US disclosed
US-20030176709-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2003-09-18 — — US disclosed
US-6569978-B2 4-(9-carbazolylmethyl)styrene monomer; homo- and co-polymers; heat resistance, optical properties, and narrow molecular weight distribution KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-05-27 — — US disclosed
US-6545159-B2 Suzuki coupling reaction of vinyl-phenylboronic acid and 2-bromopyridine in presence of alkali metallic base and tetrakis/triphenylphosphine/palladium to form styrenepyridine monomer KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-04-08 — — US disclosed
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2002-12-26 — — US disclosed
US-20020115810-A1 Anionic polymerization of functionalized styrene derivatives containing carbazole KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2002-08-22 — — US disclosed
EP-1216995-A2 Method for anionically polymerizing styrene derivatives containing carbazole as functional side group Kwangju Institute of Science and Technology (KR) 2002-06-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform VAT1, PBRM1, THEM6 CYP19A1 1670/4885LMNA 4034/4885PSMD14 1844/4885
US-20030176709-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform VAT1, PBRM1, THEM6 CYP19A1 1670/4885LMNA 4034/4885PSMD14 1844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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