SCHEMBL14494201

SCHEMBL14494201

COCN(C(=O)c1c(F)cccc1Cl)C(=O)N(COC)c1ccc(SC(F)F)cc1F

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RORC P51449 18/20 0.38
TLR7 Q9NYK1 1/20 0.34
RORA P35398 1/20 0.34
RORB Q92753 1/20 0.34
NR1H4 Q96RI1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5314390 0.82 LMNA (0.36) TLR7
SCHEMBL14494224 0.79 LMNA (0.33) RORC
SCHEMBL5314175 0.79 ATM (0.40)
SCHEMBL5316112 0.78 POLB (0.39)
SCHEMBL14494209 0.78 RORC (0.30) RORC
SCHEMBL14494230 0.76 RORC (0.33) RORCTLR7RORARORB
SCHEMBL5318469 0.75 SMN1; SMN2 (0.36)
SCHEMBL5314123 0.74
SCHEMBL14494204 0.74 GAA (0.34)
SCHEMBL5314164 0.73 GAA (0.38) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007066496-A1 BENZOYLUREA COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 WO disclosed